1-Naphthylmethcathinone

1-Naphthylmethcathinone (AMAPN) is a monoamine releasing agent of the cathinone and naphthylaminopropane families. It is an analogue of methcathinone in which the phenyl ring has been replaced with a 1-naphthalene ring.

The drug acts as a potent serotonin–norepinephrine–dopamine releasing agent (SNDRA). Its EC₅₀Tooltip half-maximal effective concentration values for induction of monoamine release are 21.6 nM for serotonin and 55.2 nM for dopamine, whereas the EC₅₀ for norepinephrine was not reported. However, AMAPN induced 92% release of norepinephrine at a concentration of 10,000 nM, indicating that it is an effective norepinephrine releaser as well.

See also

• 1-Naphthylaminopropane (1-NAP)
• 2-Naphthylmethcathinone (BMAPN)
• 2,3-Methylenedioxyamphetamine (2,3-MDA)
• 2,3-Methylenedioxymethamphetamine (2,3-MDMA)

References